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Further, in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)-treated mice, SF treatment (56.4 mol/kg/day for 10 days) attenuated dopaminergic neurotoxicity by activating BDNF and suppressing methyl CpG-binding protein 2 (MeCP2) (84) and activated Nrf2 (1 M SF) (85)

Standard protocols use 50100 mg/kg via oral gavage or supplemented drinking water, per institutional guidelines

Applied Ergonomics, 25 , 294298

p53 can inhibit ferroptosis either by downregulating SLC7A11 expression or through the p53-p21 axis, indicating a connection between apoptosis and ferroptosis [46, 47, 90]

Brager MA, Patterson MJ, Connolly JF, Nevo Z
