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Learning latency was significantly pronounced in both male and female mice treated with intranasal saline, with much slower escape times and a lower magnitude of improvement, validating the naturally occurring cognitive decline of these mice

Vasconcelos SML, Goulart MOF, Moura JBF, et al

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Researchers have also studied this mechanism in relation to muscle-tissue models and general markers of cellular aging

But it illustrates the direction the field is moving, toward multimodal enhancement strategies that combine physical and chemical approaches to maximize nasal peptide delivery