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When its severe or happens over an extended period, it can cause very disruptive symptoms that interfere with even the most routine activities
PubMed Kleinert, M., Sachs, S., Habegger, K.M., Hofmann, S.M., & Mller, T.D

Subject 3 has, in general, a lower count rate comparing to the rest on the subjects and does not show a clear heart rate peak in the frequency analysis for the late time gate

These include how bad the symptoms are, any other health issues, and how well the body absorbs B12

Excessive agitation
