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Description
higher or twice-daily dosing uses more

This method offers several advantages over other routes of administration, such as oral or intramuscular, including faster onset, higher bioavailability, and the ability to administer substances that may be poorly absorbed or tolerated by other routes
[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Salah H.M., Al'Aref S.J., Khan M.S., et al

This is a stressor for the body, causing hypoxia of intestinal cells due to redistribution of blood in the body, hyperthermia and dehydration [158, 159]

Geneva, Switzerland: ISO, 2004
