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Currently, oxidative stress and neuroinflammation remain underexplored in literature, necessitating more detailed qualitative and quantitative studies with larger cohorts

4 The Case 1 patient had hyperpigmentation over the dorsum of all the toes, similar to the type of pigmentation described by Baker et al

Fibroblasts are considered to produce extracellular matrix proteins such as fibrin, collagen, elastin, and others

Hyperhomocysteinemia in hypofertile male patients can be alleviated by supplementation with 5MTHF associated with one carbon cycle support

These networks significantly enhance depth and performance by incorporating residual and dense connections [51, 52]