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Adverse events
doi: 10.1016/j.rbmo.2010.03.008 119 LafuenteRGonzlez-ComadrnMSolILpezGBrassescoMCarrerasRet al
Reversible phosphorylation of pyruvate dehydrogenase complex mediated by calcium partly regulates the supply of reducing equivalents (NADH/NAD + ratio)
Notably, these specific genes epigenetically modified by DNA hypermethylation regulate cancer response to systemic chemotherapy, making them potential predictive markers for therapy response, as shown in Figure 2
