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Protein breakdown precedes pancreatic tumor development

In addition, the accumulation of AGE in the tissues induces cellular oxidative stress and promotes inflammation, thus increasing the vulnerability of the target tissues [58]

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FASEB J 13:411418 Hagen TM, Vinarsky V, Wehr CM, Ames BN (2000) (R)-alpha-lipoic acid reverses the age-associated increase in susceptibility of hepatocytes to tert -butylhydroperoxide both in vitro and in vivo

Anyone who suffers from high blood pressure or has orthopaedic problems should not take part in a marathon
