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To manage this risk, make sure you: Complete the full course of medication: Always finish the entire prescribed course, even if your dog seems better

However, controlled studies with histological examination of the articular cartilage have not been conducted in the large or giant breeds

Let your provider know if you do not feel any change after a month

Neurological symptoms often develop gradually and may include: Paraesthesia : tingling or 'pins and needles' sensations, typically starting in the feet and hands Numbness : reduced sensation in the extremities, which may affect balance and coordination Burning pain : particularly in the feet, often worse at night Weakness : muscle weakness and difficulty walking Balance problems : unsteady gait and increased fall risk due to proprioceptive impairment Cognitive changes : memory problems, confusion, difficulty concentrating, and mood disturbances Haematological signs may accompany neurological symptoms and include fatigue, weakness, pallor, and shortness of breath due to megaloblastic anaemia

Despite promising research, AOD 9604 has not been approved by the FDA or other major regulatory bodies for medical or therapeutic use in humans