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In response to various mitochondrial stressors, such as hypoxia, loss of mitochondrial membrane potential, and oxidative stress, mitophagy receptor proteins are engaged in the selective destruction of damaged mitochondria through their interactions with the essential autophagy protein LC3 [15, 105]

For all outcomes, the study staff have received training before initiation of the project, and the staff will be used based on their skill level

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A Multicenter Study of the Effects of Vitamin B12on Sleep-Waking Rhythm Disorders: In Shizuoka Prefecture