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Without employing non-target high-resolution mass spectrometry or toxicity assays (e.g., Microtox ) throughout the experiment, studies risk reporting a successful degradation that merely converts a parent pollutant into a different, yet still harmful, suite of compounds (rdlov et al., 2021)

doi: 10.1093/tas/txad094

Proc Natl Acad Sci U S A 110, E275284

10.2337/dbi20-0018 [DOI] [PMC free article] [PubMed] [Google Scholar] 94.Yang L, Han Y, Zhang T et al (2024) Human vascularized macrophage-islet organoids to model immune-mediated pancreatic beta cell pyroptosis upon viral infection

Specifically, recent evidence suggests that NO signaling triggers vesicle release (Wildemann and Bicker, 1999), enhances neurotransmitter release (Nickels et al., 2007), and inhibits acetylcholinesterase activity (Petrov et al., 2013)