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The emulsifying agent, carboxymethylcellulose, has been reported to alter the intestinal microbiota and promote chronic inflammation, and polysorbate 80 has been found to have an erosive impact on the intestinal mucosal layer (Chassaing et al

A broad inflammatory response and severe myelin distortion resulting from such anomalies might result in an immunological response in the CNS analogous to the pathophysiological circumstances of multiple sclerosis

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Long-Term Safety Considerations While 24-week human trials provide reassurance about short-to-medium term safety, very long-term data (multi-year continuous use) is limited

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