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The trend is real but we cannot point to one proven reason
doi: 10.3390/cells9020297

Many people do everything right and still feel stuck
Otani N, Hoshiyama E, Ouchi M, Takekawa H, Suzuki K
Just as certain genotypes influence how people metabolize nutrients, variations in gut microbiota composition could dictate how effectively individuals derive neuroprotective benefits from polyphenols and other antioxidants [127]
