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In a 24-week randomized controlled trial, curcumin reduced hepatic fat and remodeled BA signaling, suggesting a gut microbiota-dependent BA mechanism (Panahi et al., 2019)

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Screening promising therapeutic targets related to ferroptosis and potential therapeutic strategies for clinical application has become necessary and urgent
Since MTX must dissolve in neutral or basic solutions, its solubility is pH-dependent
The Wnt family proteins are growth regulators acting as ligands of Frizzled receptors in the liver
