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Peer review Peer review information Nature Reviews Endocrinology thanks Thomas Lutz and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

10.3109/03008207.2015.1040547 76 JeongC

However, severe side effects and poor target specificity remain major obstacles for the development of copper complexes as anticancer drugs

The 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (MTT) was sourced from Sigma-Aldrich

Chimeric Antigen Receptor (CAR T)-cell therapy currently approved by the FDA for treating B-cell acute lymphoblastic leukemia [98], B-cell lymphomas [99], and multiple myeloma [100] and is increasingly being administered to patients is associated with cytokine release syndrome (CRS)