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Description
Furthermore, SPH3127 exhibited higher bioactivity with more potent antihypertensive effect in preclinical models than Aliskiren due to its unique chemical structure containing methyl substituents to improve renin inhibitory activity and the replacement of the indole skeleton by 2,7-diazaindole to improve the pharmacokinetic profile [9]
Ontogenic, Immunological, and Behavioral Changes of Crack Cocaine Exposure During the Gestational Period
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10.1002/cphy.c110066 70
