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frameworks such as EU REACH (specifically Annex XIII regarding persistence and bioaccumulation) and standardised testing protocols like OECD TG 318 (dispersion stability) and TG 319 (bioaccumulation) increasingly demand a granular understanding of nanomaterial behaviour in complex aquatic matrices.28,29 Much of the existing literature has addressed the efficacy and the ecotoxicology of remediation ENMs as separate, often disconnected, fields of inquiry.24,26,27 Efficacy studies are typically performed under idealised laboratory conditions optimised for performance, while toxicity assessments are conducted using standardised protocols that may not reflect realistic exposure scenarios

In the consent form, there is a separate provision for consent of biological samples where the participants may agree or refuse

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FIGURE 16 Discussion TBI has been known to cause damage to the neurons, axons, dendrites, and microvasculature resulting in neurological dysfunction

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