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It contains a small amount of cyanide which the body must detoxify, is shorter-acting and is not recommended by NICE for clinical use

Discovery and activity of (1R,4S,6R)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1- dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4- fluorophenyl)methyl]-2-oxoethyl]-2-methyl-2- azabicyclo[2.2.2]octane-6-carboxamide (3, RY764), a potent and selective melanocortin subtype-4 receptor agonist

(the FDA has exempted many vitamins from formal categorization), but they are regarded as safe as part of a normal diet and necessary for fetal growth