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[DOI] [PubMed] [Google Scholar] 20.Cuzzocrea S, Mazzon E, Dugo L, et al

It is a more potent anticancer and anti-inflammatory agent than RES (Chiou et al., 2011) and it distributes widely among the main target organs (brain, liver, kidney, heart and lung) for what seems to be a promising (Choo et al., 2014) and safe (Riche et al., 2013) therapeutic strategy

Reproducing complex 3-D structures derived from patients in the laboratory and overcoming challenges associated with their generation, manipulation, and analysis would enable us to understand the effect of therapeutic compounds on different types of neurons and cellular populations of the nervous system and it would also allow us to investigate the role of the inflammatory/immune system in a more disease-specific and patient-transferable manner

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