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Limitations of C57BL/6J as an Experimental Model C57BL/6J mice are known to have mutations in the nicotinamide nucleotide transhydrogenase (NNT) gene, which results in mitochondrial redox abnormalities

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Between age 1 and 8 years old, the recommendation is 90 mcg of iodine

In addition, each analytical batch of study samples was processed with laboratory controls, including method blanks and standard reference materials, to monitor method performance continuously