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Toxic and essential metal interactions

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Blood 112(11):844, 2008

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Mutation of tyrosine 138 to a phenylalanine resulted in a doubling of the specific activity (Table 1) indicating a specific role for this tyrosine 27 as a gatekeeper and moderator of second substrate access

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The study also found elevated levels of oxidative stress markers, such as AGEs, and reduced activity of antioxidant enzymes, including GPx, GR, and TRxR, in Hashimotos patients

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10.1097/MD.0000000000011297 112 WanigasekaraY.KeastJ

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