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Tesamorelin (brand name Egrifta) was FDA-approved in November 2010 for reduction of excess abdominal fat in HIV-infected adults with lipodystrophy

In clinical trials, NAC supplementation reduced markers of oxidative stress by 25% and improved glycemic control, with HbA1c levels decreasing by 1.2% after six months [63]

In vivo assessment by 31P nuclear magnetic resonance spectroscopy

Therefore, 8-OHdG has become a marker for OS

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