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NO reacts with superoxide anion (O 2 ) to form a stronger oxidant identified as peroxynitrite anion (ONOO )

Wheatcroft SB, Kearney MT, Shah AM, Ezzat VA, Miell JR, Modo M, Williams SCR, Cawthorn WP, Medina-Gomez G, Vidal-Puig A, Sethi JK, Crossey PA

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What comparative research designs are used to distinguish independent versus combined effects of these two compounds
