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Antimicrobial peptides calm infection-driven inflammation not only by killing microbes, but by sending signals to immune cells to cool it

Looking forward, three key research priorities emerge: (1) Mechanistic Elucidation: Future work must precisely define organelle-specific mechanisms, particularly the potential role of lipid droplet-mitochondria cross-talk in airway epithelial cells, and validate these pathways in human COPD samples

This combination has shown greater weight loss than either therapy alone

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Kidney diseases, specifically acute kidney injury (AKI) and chronic kidney disease (CKD), represent major global health burdens.3,4 The pathophysiology of these renal diseases involves interconnected mechanisms, notably inflammation, fibrosis, and oxidative stress, with the excessive generation of reactive oxygen species playing a critical role in disease initiation and progression.5,6 Consequently, therapeutic strategies that modulate oxidative stress and associated redox-sensitive signaling pathways are increasingly relevant to nephrological research and clinical practice