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Therefore, it is suggested that this mechanism may represent a novel therapeutic strategy in the treatment of atopic dermatitis (AD) [176]

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2+3), Doxorubicin-induced senescent cells showed an upregulation in FOXO4 foci (Fig.4B+C) and FOXO4-DRI potently and selectively lowered the viability of Doxorubicin-senescent vs

Its unique peptide-metal structure provides researchers with a valuable model for investigating metal-dependent biological processes and the integration of signaling pathways within complex laboratory systems

System Xc - is a 1:1 heterodimer composed of SLC3A2 and SLC7A11 subunits, localized on the plasma membrane, and functions as an antiporter exchanging one molecule of extracellular cystine (Cys 2 ) for one molecule of intracellular glutamate (Glu), thereby mediating cystine uptake