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Inflammatory mediators can induce production of prostaglandin E 2 (PGE 2 ) and NO, which in turn have the capacity to promote maturation and increase transport of melanosomes, to upregulate the expression of the tyrosinase gene, and to increase the complexity of the network of melanocytic dendrites

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These unregulated Melanotan products may contain contaminants or be incorrectly dosed, posing further unknown health risks

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Based on reported side effects, Melanotan 1 has the narrower, milder profile because it targets a single receptor

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Mayo Clinic also notes bismuth subsalicylate can cause gray-black stools that go away after stopping

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Original article on LiveScience

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