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Moreover IGF-1 was tested in patients with osteopenia/osteoporosis linked to anorexia nervosa and severe bone fractures with positive results utilising doses ranging from 30 g to 1 mg/kg/day for 29 months [274, 275]

This is the difference between losing weight and keeping it off

These complexities are further underscored by a recent report by Soriani et al., which suggests that CD38 can act as a decoy for extracellular cGAMP, a mediator of innate immunity
So maybe save your time (and your money), because antibodies are only part of the immunity story

doi:10.1016/S0895-4356(00)00340-1 160