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Clinical intervention studies have shown that supplementation with vitamin D3, combined with vitamins B6 and K1, effectively alleviates oxidative stress (93), and meta-analyses support its potential to improve depressive symptoms (94)

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31 , 33 , 34 mTORC1 is a protein complex that senses the availability of nutrients, growth Factors, and the presence of cellular stresses to coordinately regulate multiple physiological cellular processes like cell growth, proliferation, autophagy, organelle biogenesis, and Wnt signaling
