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Typically resulting from mutations in TSC1 or TSC2, dominantly inherited tuberous sclerosis is associated with spontaneously resolving cardiac rhabdomyomas in infants and renal angiomyolipoma, including the malignant epithelioid variant, as well as pulmonary lymphangiomyomatosis

*** Silas Deane was a native of Groton, Connecticut

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furthermore, test animals who were fed large amounts of acrylonitrile in their drinking water developed significantly lower body weight and other adverse effects, including lesions in the central nervous system and growths in the ear ducts. The FDA banned acrylonitrile beverage containers in March of 1977
