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Therefore, the problem that the agents successful in pre-clinical experimental autoimmune encephalitis trials, were either less effective in patients, worsened disease or caused unexpected, severe adverse events (60), may be at least partly solved with the more suited cuprizone model that reflects a toxic experimental model (12)

Individual results vary, and are not guaranteed

10.3892/ijmm.2016.2625 201 ShengJ.WangL.HanY.ChenW.LiuH.ZhangM.et al (2018)

Inflammation: Measurable reduction in inflammatory markers and edema within 37 days across multiple tissue injury models (Seiwerth et al., 2018)

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