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It is vital to prevent excitotoxicity from causing damage in patients with neurodegenerative diseases

Osteoarthr Cartil Open

Emerging evidence indicates that lactate serves as an immunomodulator [288] and mediates differentially expressed gene production [289], revealing that lactate may be the white swan of reshaping energy metabolism rather than a glycolytic waste product. Metabolites derived from nonimmune cells have been confirmed to affect the glycolysisOXPHOS axis of immune cells and then reshape their phenotype [290]

By looking at the gene expression patterns, Li's team first found that the pathway that produces vitamin B12 was significantly altered in the skin bacteria of people with acne, compared with the skin bacteria of people without acne