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doi: 10.1089/ars.2010.3275

Down-stream, dendritic cells exposed to smoke migrate poorly to lymph nodes and bias T-cell priming away from protective Th1 immunity, favouring Th2, Th17, and regulatory T-cell profiles marked by exhaustion receptors such as PD-1 and CTLA-4 (McNab et al., 2011

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In higher eukaryotes GCL is a heterodimer comprising a catalytic (GCLC) and a modifier (GCLM) subunit 7
