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Description
Melatonin counteracts lipopolysaccharide-induced expression and activity of mitochondrial nitric oxide synthase in rats

It means the body is dealing with more reactive molecules than it can easily keep in balance

It inhibits the folate cycle, leading to AMPK activation, which is essential for maintaining metabolic homeostasis 3

doi: 10.1158/1940-6207.Capr-13-0120

The two studies are similar in concept but, honestly, cant be directly compared since their methods differ
