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Description
Nature, 508(7495), 258262

Early exploratory studies have examined whether AOD9604's signaling properties could support connective tissue repair under mechanical stress, and a rabbit osteoarthritis model study investigated intra-articular injection of AOD9604, in some cases alongside hyaluronic acid, as a research approach to joint tissue changes

High-Dose Oral Protocol (Daily) Oral doses are typically administered once daily

(PubMed) Mazokopakis EE, Starakis IK

About 90% improve within four months using conservative approaches like chiropractic care, physical therapy, and smart lifestyle changes
