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At 24 h post-transfection, cells incubated with TUNEL reaction mixture (37 C, 1 h, dark)

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2B also suggest a gross change in the tertiary structure because of the observed decrease in CD signals at 269, 279, and 289 regions

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Individualized titration is essential to achieve serum trough levels in the mid-normal physiologic range, thereby minimizing adverse effects such as erythrocytosis, gynecomastia due to aromatization, or suppression of endogenous spermatogenesis

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It is closely linked to the phenotypic heterogeneity of cancer cells and helps them rapidly adapt to various injuries, facilitating drug resistance [114]

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