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It is important as the liver plays a key role in filtering harmful substances from the body

Three participants have been dosed, as well as a fourth patient with a related X-linked genetic immunodeficiency, CD40L-deficient Hyper IgM

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Sulfasalazine treatment also decreased the expression of Cd4 (a T-cell marker) and Cd19 (a B-cell marker), consistent with the suppression of the formation of TLS (Figure 4E)

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