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Discussion In vitro sperm production with PRGF supplemented media In vitro generation of functional sperm remains a long-standing scientific challenge

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Fang G, Zhang Q, Pang Y, Thu HE, Hussain Z (2019) Nanomedicines for improved targetability to inflamed synovium for treatment of rheumatoid arthritis: multi-functionalization as an emerging strategy to optimize therapeutic efficacy

Therefore, it can be deduced that the interaction between these molecules are complex and cause multidirectional alterations in the structure of the protein