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doi: 10.1046/j.1365-2125.2003.01875.x 160 RougheadEEGilbertALPrimroseJGSansomLN
Food and Drug Administration (FDA) has approved 14 ADCs for clinical use, and over one hundred new ADC drugs are under development [24-26]
It is synthesized primarily in the liver, though individual cells can help regulate their own intracellular glutathione levels based on metabolic need
In self-injection, hand washing, alcohol swabs, and disposables reduce infection risk
These ongoing challenges of skin phototoxicity, targetadjacent healthy tissue photosensitizer accumulation and associated offtarget photosensitivity require innovations in photosensitizer design that improve PDT selectivity
