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Indeed, we found hypotaurine and serine levels increased in the liver of Gclc KO mice (Fig

These distinguished effects may be attributed to the TME modulation capacity of H-MnO 2 -based nano-platform and the subsequently enhanced chemo-PDT treatment to induce the release of tumor-associated antigens 49, 50 , which would activate dendritic cells and then the recruitment of effector T cells into tumors