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These transporters are particularly relevant for the metabolism of several 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins), which are used in the treatment of hypercholesterolemia

Ongoing efforts by researchers to further optimize metabolic targeting within a personalized treatment framework may have the potential to transform the therapeutic landscape of this otherwise devastating disease

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Since it is an exogenous androgen, it should not be used in men trying to conceive