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In a highly prevalent condition like MASH, enabling simple, scalable access to clinically validated testing is essential to identify at-risk patients earlier in routine care, including in primary care and endocrinology settings, says Pejvack Motlagh, chief medical officer at GENFIT, in a release
TrxR, thioredoxin reductase Graphical abstract Highlights Thiol-mediated signalling is a central node in the cellular redox network
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To elucidate the role of GST and SULT against AITC, the protein (GST and SULT) and ligand (AITC) interactions were studied in the current investigation and it was found that leucine and aspartic acid are the key amino acids in mediating GST-AITC and SULT-AITC interaction, respectively
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