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doi: 10.3389/fimmu.2023.1117760 28 SefikEQuRJunqueiraCKaffeEMirzaHZhaoJet al

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(2017) found four PL species, including oxygenated AA and AdA-containing PE species, are crucial for ferroptotic death signaling (C18:0/C20:4 and C18:0/C22:4)

This requires a dual stratification system: biological, such as MDF, Lille, and MELD, to predict mortality, and psychosocial, such as the Stanford Integrated Psychosocial Assessment for Transplantation tool and the sustained alcohol use post-liver transplant score [113,114]

These toxic elements thus induce a series of inflammatory cascades, leading to mobilization of microglia and astrocytes and increased production of cytokines and chemokines (Mehta et al