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NNMT is an enzyme that works in your cells to manage energy and metabolism

In mice, a high-fat diet has also been shown to impair leptin signaling by attenuating STAT3 activation, thus contributing to leptin resistance [18].Leptin receptor activation engages intracellular proteins, such as protein tyrosine phosphatase1 B (PTP1B) and suppressor of cytokine signaling-3, that terminate receptor signaling

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Zukin R.S

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