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Downstream of insulin and AKT, mTORC1 suppresses sortilin, leading to an increase in apoB secretion (10)

Doxycycline hydrochloride induces apoptosis , inhibits autophagy and EMT , downregulates stem cell markers, and activates the PI3K-AKT pathway, thereby effectively inhibiting the viability and proliferation of cancer cells such as breast cancer cells

10.1016/j.cell.2010.01.040 [DOI] [PubMed] [Google Scholar] Schugar R

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Toll-like receptors and NLRP3 inflammasome-dependent pathways in Parkinson's disease: mechanisms and therapeutic implications
