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Description
For further prognostic evaluation and clinical decision-making, breast cancer can be classified into three subgroups based on immunohistochemical staining results for ER, PR, and HER2: HR-positive/HER2negative (HR+/HER2, ~70%), HER2positive (HER2+, ~1520%), and triple-negative breast cancer [TNBC, HR-negative (HR-), HER2, ~15%]

Key Takeaway: Glutathione is the bodys primary internal defense against oxidative stress, but it exists in "active" and "spent" states

Science 360 , 751758 (2018)
Recently, this was confirmed by Seeley et al., which in addition showed the spatial location of metabolites revealing the differential presence of lactic acid in the necrotic core of stable plaques, while pyruvic acid was more prevalent in the fibrous cap

Currently, oral PDE5I is the first-line treatment of ED which has the advantages of high safety and good effect
