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SIRT1 acts in this way by deacetylating it
N., Ngwa, V

Short-chain fatty acids protect against high-fat diet-induced obesity via a PPAR-dependent switch from lipogenesis to fat oxidation
97 YasudaY.HaraS.HirohataT.KoikeE.YamasakiH.OkumotoK.et al (2010)
Association between IRS1 Gene Polymorphism and Autism Spectrum Disorder: A Pilot Case-Control Study in Korean Males
