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25 IC/BPS patients with widespread pain had more severe urologic symptoms, worse psychosocial symptoms and functioning, poorer QoL, and a worsening symptom trajectory over time

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As autophagy-related genes are highly expressed in early AD, enhanced autophagy may be a promising research area for achieving neuroprotection in AD patients (Moujalled et al., 2021)

Collectively, these studies established -glucuronidase-cleavable linkers as a versatile and chemically adaptable class within the broader family of enzyme-responsive ADC linkers

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