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Because the body stores only limited amounts of many B vitamins, maintaining healthy levels is important for overall wellness

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Adverse Events/Precautions Rare, but devastating long-term adverse effects of LIS including physical disfigurement and the off-label manner of administration have prevented widespread use of medical-grade LIS

It can further regulate the HPA axis that responsible for stress response and the autonomic nervous system (Han et al., 2022)

It shows why the combination question needs medical context