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SIRT1 influences critical hepatic processes by deacetylating key transcription factors and enzymes involved in glucose and lipid metabolism, inflammation, DNA repair, mitochondrial function, cell proliferation, and cellular senescence (Wu et al., 2022

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doi: 10.1007/s10689-013-9664-5 8 LuKHDinhMKohlmannWWatsonPGreenJSyngalSet al
