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Importantly, combining NDBs with antibiotics has synergistic effects, significantly enhancing antibacterial activity and reducing the required antibiotic dosage (Si et al., 2021
The medication received marketing authorization in the European Union through the Decentralized Procedure in the third quarter of 2022

[DOI] [PubMed] [Google Scholar] Berthold EC, Kamble SH, Raju KS, King TI, Popa R, Sharma A, Len F, Avery BA, McMahon LR, McCurdy CR (2021) Preclinical pharmacokinetic study of speciociliatine, a kratom alkaloid, in rats using an UPLC-MS/MS method
