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You might need them to manage ongoing health problems
In adipose tissue, proinflammatory response decreased concurrently with an increase in anti-inflammatory M2 macrophage gene expression

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Koppe T, Patchen B, Cheng A, Bhasin M, Vulpe C, Schwartz RE, Moreno-navarrete JM, Fernandez-real JM, Pissios P, Fraenkel PG (2017) Nicotinamide N -methyltransferase expression decreases in iron overload, exacerbating toxicity in mouse hepatocytes
